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Project Biological procedures for diagnosing the status and predicting evolution of

Project number 3998
Geographical coverage Germany, Spain, Denmark, Switzerland, Czech Republic
Budget (in €) 2665000
Programme INCO MED (FP6)
Web site
Objectives - The objective of BIOTOOL is the generation and validation of novel conceptual and material instruments, rooted in biological processes, for diagnosing soil status and predicting evolution of contaminated soil and groundwater. The focus is on the assessment and evaluation
of natural attenuation processes. This will require benchmarked monitoring tools and warning criteria to implement natural attenuation as the key groundwater and soil remediation strategy in Europe. It will be materialized through the application of a suite of state-of-the-art
genomic, proteomic and analytical technologies to environmental samples and sites themselves. We will exploit the translocation of indicator chemicals from below ground into above-ground vegetation as a cheap and rapid monitoring tool for subsurface contamination.

- Diagnosis of the biological status and evolution models for polluted environments will be achieved through [i] the design and utilization of DNA and specifically DNA-array technology for examining the catabolic potential of any given particulate sample and [ii] the identification of protein biomarkers as descriptors of soil and groundwater quality and biological attenuation clocks. The progress in  microbial community functional genomics and proteomics will be employed to gain a mechanistic understanding of prevailing stresses, global responses to chemical insults, plant/microbe interactions and microbial community adaptations that determine microbial-driven soil and groundwater  processes. This will add a considerable predictive power to the genomic and proteomic approaches mentioned above.

Determining the links between environmental factors and expression of degradation abilities will be crucial for strategies aiming at an optimal expression of the catalytic power of the indigenous microbial community. The robustness of diagnostic instruments for future normative applications will be validated in microcosms and used for ass.
Period [01/09/2004 - 01/09/2007]


  • Gesellschaft für Biotechnologische Forschung mbH
    Country Germany
    Contact Mr. Helmut Pieper Dietmar,
    Position: General coordinator of the project
    Phone/fax: ,

Funding sources

  • European Commission
    Source EC INCO MED
    Programme INCO MED
    Funding rate 67